Analyzing the Relationship between Dialysate Flow Rate Stability and Hemodialysis Machine Efficiency

Keywords: Hemodialisis, Dialysate, Flow Rate, Flow Sensor

Abstract

Chronic kidney disease (CKD) is a condition characterized by impaired kidney function, leading to disruptions in metabolism, fluid balance, and electrolyte regulation. Hemodialysis serves as a supportive therapy for individuals with CKD, prolonging life but unable to fully restore kidney function. Factors influencing urea and creatinine levels in hemodialysis patients include blood flow velocity, dialysis duration, and dialyzer selection. This research aims to establish a standard for calculating the dialysate flow rate, thereby enhancing dialysis efficiency. The study employs a pre-experimental "one group post-test" design, lacking baseline measurements and randomization, although a control group was utilized. The design's weakness lies in the absence of an initial condition assessment, making conclusive results challenging. Measurement comparisons between the module and the instrument yielded a 5.30% difference, while the difference between the hemodialysis machine and standard equipment was 4.02%. Furthermore, six module measurements against three comparison tools showed a 0.17% difference for the hemodialysis machine with standard equipment, and a 0.18% difference for the module with standard equipment, with a 0.23% discrepancy between the two. Further analysis is necessary to understand the clinical significance and implications of these measurement variations on overall dialysis efficacy

Downloads

Download data is not yet available.

References

F. Husain, H. Kusuma, and A. Johan, “Effects of Peer Support Program on Self-Management in Patients with End-Stage Renal Disease Undergoing Hemodialysis,” J. Nurs., vol. 10, no. 2, pp. 171–181, 2020, doi: 10.14710/nmjn.v10i2.26502.

M. Rocco et al., “KDOQI Clinical Practice Guideline for Hemodialysis Adequacy: 2015 Update,” Am. J. Kidney Dis., vol. 66, no. 5, pp. 884–930, 2015, doi: 10.1053/j.ajkd.2015.07.015.

P. F. Wiliyanarti, D. Komunitas, and S. Majapahit, “Life Experiance Of Chronic Kidney Disease Undergoing Hemodialysis,” NurseLine J. Vol. 4 No. 1 Mei 2019 p-ISSN 2540-7937 e-ISSN 2541-464X, vol. 4, no. 1, 2019.

A. Anjarwati et al., “Health Related-Quality of Life in CKD and Dialysis Patients in Asian Countries : A Systematic Review,” J. ARKESMAS, vol. 3, no. 2, pp. 50–55, 2018.

Z. L. Dewi, “Exploring Self-Regulation of Patients with Chronic Kidney Disease Undergoing Hemodialysis,” J. Pshychology, vol. 48, no. 2018, pp. 1–15, 2021, doi: 10.22146/jpsi.61144.

D. A. Pradila, M. P. Satiadarma, and U. S. Dharmawan, “Resilience of Elderly Patients with Chronic Kidney Disease Undergoing Hemodialysis,” J. Fac. Psychol. Tarumanagara Univ., vol. 6, pp. 1–6, 2013.

N. K. Maurya, “A REVIEW : NUTRITION IN CHRONIC KIDNEY DISEASE PATIENTS : International Journal of Advance and Innovative Research International Journal of Advance and Innovative Research,” Int. J. Adv. Innov. Res., vol. 5, no. 3, pp. 97–108, 2018, doi: 10.5281/zenodo.1423081.

J. B. Chen, K. C. Wu, S. H. Moi, L. Y. Chuang, and C. H. Yang, “Deep learning for intradialytic hypotension prediction in hemodialysis patients,” IEEE Access, vol. 8, pp. 82382–82390, 2020, doi: 10.1109/ACCESS.2020.2988993.

W. M. Azhar Bin Wan Ibrahim, “Conceptual design of blood pressure monitoring for old haemodialysis machine,” in International Conference on Computer Medical Applications, ICCMA 2013, 2013, pp. 1–5, doi: 10.1109/ICCMA.2013.6506153.

Y. T. Wulansari, “DESCRIPTION OF DEPRESSION SYMPTOMS IN HEMODIALYSIS PATIENTS AT,” J. Epidemiol. Dep. Fac. Public Heal., no. July 2019, pp. 304–314, 2020, doi: 10.20473/ijph.vl15il.2020.304-314.

S. Mandolfo, F. Malberti, E. Imbasciati, P. Cogliati, and A. Gauly, “Impact of blood and dialysate flow and surface on performance of new polysulfone hemodialysis dialyzers,” Int. J. Artif. Organs, vol. 26, no. 2, pp. 113–120, 2003.

M. Faye et al., “Manual Individualization of the Dialysate Flow According to Blood Flow : Effects on the Hemodialysis Dose Delivered and on Dialysate Consumption,” reserach Sq., vol. 6, pp. 1–5, 2020.

M. A. Ramón et al., “Original article What is the optimum dialysate flow in post-dilution online haemodiafiltration ? ଝ,” Nefrol. (English Ed., vol. 35, no. 6, pp. 533–538, 2016, doi: 10.1016/j.nefroe.2015.04.005.

R. Mcquillan, L. Trpeski, S. Fenton, and C. E. Lok, “Modifiable Risk Factors for Early Mortality on Hemodialysis,” Int. J. Nephrol., vol. 2012, p. 6, 2016, doi: 10.1155/2012/435736.

M. H. Lai, H. M. Nieh, T. P. Teng, J. J. Chen, Y. Y. Huang, and Y. C. Lu, “Development of an hemodialysis simulator for interdisciplinary learning,” in 2010 IEEE International Conference on Industrial Engineering and Engineering Management, Dec. 2010, pp. 2493–2497, doi: 10.1109/IEEM.2010.5674325.

R. DeCarlo and C. Meirina, “Parameter identification and adaptive control of an ultrafiltration process in hemodialysis,” in Proceedings of the American Control Conference, 2000, vol. 5, no. June, pp. 2967–2971, doi: 10.1109/acc.2000.879109.

R. A. Sherman, E. F. Faustino, A. S. Bernholc, and R. P. Eisinger, “Effect of Variations in Dialysate Temperature on Blood Pressure During Hemodialysis,” Am. J. Kidney Dis., vol. 4, no. 1, pp. 66–68, Jul. 1984, doi: 10.1016/S0272-6386(84)80029-3.

D. A. Elliott, “Hemodialysis.,” Clin. Tech. Small Anim. Pract., vol. 15, no. 3, pp. 136–148, 2000, doi: 10.1053/svms.2000.18297.

P. E. Pérgola, N. M. Habiba, and J. M. Johnson, “Body temperature regulation during hemodialysis in long-term patients: is it time to change dialysate temperature prescription?,” Am. J. Kidney Dis., vol. 44, no. 1, pp. 155–165, Jul. 2004, doi: 10.1053/j.ajkd.2004.03.036.

M. Robson, D. G. Oreopoulos, S. Izatt, R. Ogilvie, A. Rapoport, and G. A. Deveber, “Influence of exchange volume and dialysate flow rate on solute clearance in peritoneal dialysis,” Kidney Int., vol. 14, no. 5, pp. 486–490, 1978, doi: 10.1038/ki.1978.153.

M. Hauk, M. K. Kuhlmann, W. Riegel, and H. Köhler, “In vivo effects of dialysate flow rate on Kt/V in maintenance hemodialysis patients,” Am. J. Kidney Dis., vol. 35, no. 1, pp. 105–111, 2000, doi: 10.1016/S0272-6386(00)70308-8.

R. M. Hakim, M. A. Pontzer, D. Tilton, J. M. Lazarus, and M. N. Gottlieb, “Effects of acetate and bicarbonate dialysate in stable chronic dialysis patients,” Kidney Int., vol. 28, no. 3, pp. 535–540, 1985, doi: 10.1038/ki.1985.161.

A. Cle and V. Kovacic, “The assessment of hemodialysis technical efficacy,” J Nephrol, vol. 14, no. 1, pp. 1–9, 2004, [Online]. Available: http://journals.lww.com/ijon.

L. Dai et al., “Impact of twice- or three-times-weekly maintenance hemodialysis on patient outcomes,” Med., vol. 20, no. November 2019, 2020.

P. Zhang, J. Sun, G. Wan, and W. Liu, “Primary design of hemodialysis machine detector calibration equipment,” in 2015 8th International Conference on Biomedical Engineering and Informatics (BMEI), Oct. 2015, pp. 376–380, doi: 10.1109/BMEI.2015.7401533.

M. K. Smolek, S. D. Klyce, and J. K. Hovis, “The Universal Standard Scale: Proposed improvements to the American National Standards Institute (ANSI) scale for corneal topography,” IVth Annu. Congr. Res. Refract. Eye Surg. Technol. Ft. Lauderdale, vol. 109, no. 2, pp. 361–369, 2002, doi: 10.1016/S0161-6420(01)00888-0.

Published
2023-05-30
How to Cite
[1]
B. A. Baharsyah, E. D. Setioningsih, S. Luthfiyah, and W. Caesarendra, “Analyzing the Relationship between Dialysate Flow Rate Stability and Hemodialysis Machine Efficiency”, Indones.J.electronic.electromed.med.inf, vol. 5, no. 2, pp. 86-91, May 2023.
Section
Research Article